Identification, classification and labeling of the health hazards of a propisochlor herbicide

Abstract

According to the results obtained, the herbicide based on propisochlor is classified as hazard class 4 for acute toxicity when administered intragastrically and applied to the skin, and for inhalation toxicity it is classified as hazard class 3. It has been established that the drug has a mild irritating effect on the skin of rats (class 3B), has an irritating effect on the mucous membranes of the eyes of rabbits (class 3A), does not have a sensitizing effect (class 4), and is assigned to class 4 based on the cumulative effect.

Based on the results of a comprehensive toxicological and hygienic assessment of the formulation and active substance, the propisochlor-based herbicide is classified as a moderately hazardous substance (hazard class 3) in accordance with the Unified Sanitary-Epidemiological and Hygienic Requirements for Products (Goods) Subject to Sanitary-Epidemiological Surveillance (Control) (Chapter II; Section 15. Requirements for pesticides and agrochemicals) for handling and for highly hazardous substances (hazard class 2) in accordance with GOST 12.1.007-76 SSBT for the production process.

It is recommended to include the following health hazard markings on the container label of the drug: pictogram: exclamation point, signal word: «Warning)!», brief hazard statement: H332: Harmful if inhaled; H316: Causes mild irritation in contact with skin; H320: Causes irritation in contact with eyes.